ea0032p1088 | Thyroid cancer | ECE2013
Pignatti Elisa
, Vighi Eleonora
, Roncati Luca
, Kara Elda
, Porcheddu Eleonora
, Magnani Elisa
, Rochira Vincenzo
, Maiorana Antonino
, Carani Cesare
, Simoni Manuela
Introduction: Follicular thyroid carcinomas (FTC) are the second most common type of thyroid malignancy. Micro-RNAs (miRNAs) are a new class of small, noncoding RNAs whose expression is deregulated in many types of human cancers and may lend novel clues to FTC genesis. Pre-miR146a represents one of the most up-regulated miRNAs in papillary thyroid carcinomas (PTC) and a SNP (rs2910164), identified in pre-miR146a, contributes to genetic predisposition to PTC, but data on FTC ar...